Lots of research based on drug designing as well as in silico study, cell culture/animal model study, and the clinical trials are being conducted perceive the suitable therapeutic drugs and to develop vaccines in order to alleviate the ongoing COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although there are still no vaccines, some potential anti-viral drugs have been discovered of which remdesivir has been so far mostly accepted for the treatment purpose because of its multi-target actions. In addition to remdesivir, dexamethasone has been noticed with the capacity to protect the severely affected COVID-19 patients from death to some extent. Current review thus emphasized on both remdesivir and dexamethasone as the successful remedies for the ongoing pandemic; and projected on the possible mode of action of dexamethasone.
Rashed Noor, Yusra Binte Sikandar and Syed Abdullah Ibn Asaduzzaman